Mar 2014


The DEAD-box helicase DDX3 substitutes for the cap-binding protein eIF4E to promote compartmentalized translation initiation of the HIV-1 genomic RNA.
Soto-Rifo R*, Rubilar PS, Ohlmann T*.
Nucleic Acids Res. 2013 Jul;41(12):6286-99. doi: 10.1093/nar/gkt306. Epub 2013 Apr 28.
*Corresponding authors

The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism.
Soto-Rifo R*, Ohlmann T.
Wiley Interdiscip Rev RNA. 2013 Jul-Aug;4(4):369-85. doi: 10.1002/wrna.1165. Epub 2013 Apr 18.
*Corresponding author

miRNA repression of translation in vitro takes place during 43S ribosomal scanning.
Ricci EP*, Limousin T*, Soto-Rifo R*, Rubilar PS, Decimo D, Ohlmann T.
Nucleic Acids Res. 2013 Jan 7;41(1):586-98. doi: 10.1093/nar/gks1076. Epub 2012 Nov 17.
*Co-first authors, equal contributions

Translation initiation is driven by different mechanisms on the HIV-1 and HIV-2 genomic RNAs.
de Breyne S, Soto-Rifo R, López-Lastra M, Ohlmann T.
Virus Res. 2013 Feb;171(2):366-81. doi: 10.1016/j.virusres.2012.10.006. Epub 2012 Oct 16. Review.


DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs.
Soto-Rifo R, Rubilar PS, Limousin T, de Breyne S, Décimo D, Ohlmann T.
EMBO J. 2012 Sep 12;31(18):3745-56. doi: 10.1038/emboj.2012.220. Epub 2012 Aug 7.

The Andes hantavirus NSs protein is expressed from the viral small mRNA by a leaky scanning mechanism.
Vera-Otarola J, Solis L, Soto-Rifo R, Ricci EP, Pino K, Tischler ND, Ohlmann T, Darlix JL, López-Lastra M.
J Virol. 2012 Feb;86(4):2176-87. doi: 10.1128/JVI.06223-11. Epub 2011 Dec 7.

Different effects of the TAR structure on HIV-1 and HIV-2 genomic RNA translation.
Soto-Rifo R, Limousin T, Rubilar PS, Ricci EP, Décimo D, Moncorgé O, Trabaud MA, André P, Cimarelli A, Ohlmann T.
Nucleic Acids Res. 2012 Mar;40(6):2653-67. doi: 10.1093/nar/gkr1093. Epub 2011 Nov 24.

Functional mechanisms of the cellular prion protein (PrP(C)) associated anti-HIV-1 properties.
Alais S, Soto-Rifo R, Balter V, Gruffat H, Manet E, Schaeffer L, Darlix JL, Cimarelli A, Raposo G, Ohlmann T, Leblanc P.
Cell Mol Life Sci. 2012 Apr;69(8):1331-52. doi: 10.1007/s00018-011-0879-z. Epub 2011 Nov 11.


Activation of a microRNA response in trans reveals a new role for poly(A) in translational repression.
Ricci EP, Limousin T, Soto-Rifo R, Allison R, Pöyry T, Decimo D, Jackson RJ, Ohlmann T.
Nucleic Acids Res. 2011 Jul;39(12):5215-31. doi: 10.1093/nar/gkr086. Epub 2011 Mar 8.


The 3' untranslated region of the Andes hantavirus small mRNA functionally replaces the poly(A) tail and stimulates cap-dependent translation initiation from the viral mRNA.
Vera-Otarola J, Soto-Rifo R, Ricci EP, Ohlmann T, Darlix JL, López-Lastra M.
J Virol. 2010 Oct;84(19):10420-4. doi: 10.1128/JVI.01270-10. Epub 2010 Jul 21.


Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein.
Charnay N, Ivanyi-Nagy R, Soto-Rifo R, Ohlmann T, López-Lastra M, Darlix JL.
Retrovirology. 2009 Aug 11;6:74. doi: 10.1186/1742-4690-6-74.

Structural and functional diversity of viral IRESes.
Balvay L, Soto Rifo R, Ricci EP, Decimo D, Ohlmann T.
Biochim Biophys Acta. 2009 Sep-Oct;1789(9-10):542-57. doi: 10.1016/j.bbagrm.2009.07.005. Epub 2009 Jul 24. Review.


Lentiviral RNAs can use different mechanisms for translation initiation.
Ricci EP, Soto Rifo R, Herbreteau CH, Decimo D, Ohlmann T.
Biochem Soc Trans. 2008 Aug;36(Pt 4):690-3. doi: 10.1042/BST0360690.


Back to basics: the untreated rabbit reticulocyte lysate as a competitive system to recapitulate cap/poly(A) synergy and the selective advantage of IRES-driven translation.
Soto Rifo R, Ricci EP, Décimo D, Moncorgé O, Ohlmann T.
Nucleic Acids Res. 2007;35(18):e121. Epub 2007 Sep 18.

Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.
Dieterich K, Soto Rifo R, Faure AK, Hennebicq S, Ben Amar B, Zahi M, Perrin J, Martinez D, Sèle B, Jouk PS, Ohlmann T, Rousseaux S, Lunardi J, Ray PF.
Nat Genet. 2007 May;39(5):661-5. Epub 2007 Apr 15.