Deciphering the atlas of the HIV-1 genomic mRNP

We are starting a new project aimed to isolate and characterize the whole components of the HIV-1 gRNA-containing mRNP. This project, funded by the Department of International Relationships (DRI) of Conicyt, will be carried out in tight collaboration with Drs. Melissa Moore and Emiliano Ricci from the University of Massachusetts Medical School.
The main goal of this project is to perform pull-downs of the HIV-1 gRNA (from nuclear and cytoplasmic factions, under different conditions, etc) and analyze both the proteins associated by Mass Spectrometry and the regulatory RNAs (miRNAs, lncRNAs, etc) by deep-sequencing.

HIV-1 mRNPs identification